![]() Subgroup analyses by type of onset and preoperative neurological status were also performed to determine specific characteristics of patients who might benefit from NBP administration. The incidence of perioperative stroke and transient neurological deficit (TND) and the severity of neurological deficits were compared between 49 propensity score-matched case pairs with or without NBP treatment. The overall study group included 164 patients (213 surgically treated hemispheres), including 49 patients who received NBP (25 mg twice daily) for 7 postoperative days. The authors studied cases in which patients underwent combined revascularization surgery for MMD at their institution, with or without NBP administration. This pilot study evaluated the effect of NBP on perioperative stroke and neurological deficits in patients with MMD. dl-3-n-butylphthalide (NBP) is approved for the treatment of ischemic stroke in China. Postoperative neurological deficits impair the overall outcome of revascularization surgery for patients with moyamoya disease (MMD).
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